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5. Nanoparticle-coated Salmonella as Oral DNA Vaccines for Cancer Immunotherapy

Nanoparticle-coated Salmonella as Oral DNA Vaccines for Cancer Immunotherapy

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：water15

【摘 要】

：

Although oral delivery of DNA vaccine has drawn extensive attentions and represents one of the most promising approaches for cancer immunotherapy;however,the low efficiency of DNA transfection is the

【作 者】

：

Yuan Ping Qinglian Hu Min Wu Guping Tang Chuanbin Wu 

【机 构】

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School of Pharmaceutical Sciences,Sun Yat-Sen University,Guangzhou 510006,China

【出 处】

：

Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

：

2016年11期

【关键词】

：

vaccine delivery nanomedicine Salmonellae phagosomal escape 

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　　Although oral delivery of DNA vaccine has drawn extensive attentions and represents one of the most promising approaches for cancer immunotherapy;however,the low efficiency of DNA transfection is the major bottleneck that severly hampers the efficacious immune response.

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