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5. Design,synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as

Design,synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as

来源 :2015年全国药物化学学术会议暨第五届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：zhgjdy

【摘 要】

：

In continuation of our efforts toward the discovery of potent HIV-1 NNRTIs with novel structures,a series of novel imidazopyridinylthioacetanilide derivatives were rationally designed via scaffold hop

【作 者】

：

Xiao Li Peng Zhan Xinyong Liu 

【机 构】

：

Department of Medicinal Chemistry,School of Pharmaceutical Sciences,Shandong University,44,West Cult

【出 处】

：

2015年全国药物化学学术会议暨第五届中英药物化学学术会议

【发表日期】

：

2015年3期

【关键词】

：

HIV NNRTIs Heterocycle imidazopyridine Scaffold hopping 

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　　In continuation of our efforts toward the discovery of potent HIV-1 NNRTIs with novel structures,a series of novel imidazopyridinylthioacetanilide derivatives were rationally designed via scaffold hopping strategy,and then were synthesized and evaluated for their anti-HIV activities in MT-4 cells.

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