【摘 要】
：
Clostridium difficile (Cd) is a well known emerging pathogen of opportunistic infection in hospitals worldwide and is the major causative antibiotic-associated pseudo-membranous colitis and diarrhea i
【机 构】
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National Health Research Institutes Taiwan
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Clostridium difficile (Cd) is a well known emerging pathogen of opportunistic infection in hospitals worldwide and is the major causative antibiotic-associated pseudo-membranous colitis and diarrhea in human, because of two large protein toxins, toxin A and toxin B, that disrupt intestinal epithelial cells.Morbidity and mortality of Cd-associated disease have increased significantly due to multi-drug resistant strains.
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