【摘 要】
：
Complement system, as the important part of innate immunity and one of the major effecter arms of immune responses, play a critical role in innate immune de
【机 构】
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KeylaboratoryofExperimentalMarineBiology,InstituteofOceanology,ChineseAcademyofSciences,Qingdao,Chin
【出 处】
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18th International Pectinid Workshop(第18届国际扇贝研讨会)
论文部分内容阅读
Complement system, as the important part of innate immunity and one of the major effecter arms of immune responses, play a critical role in innate immune defense of invertebrates.In present study, the full-length cDNA of thioester-containing protein (CfTEP), C1q-domain-containing protein (CfC1qDC, AiC1qDC-1~AiC1qDC-5), C-type lectins (Cflec-1~Cflec-5, Ailec-1~lec-9) and fibrinogen-related protein (AiFREP) were cloned from scallop Argopecten irradians and Chlamys farreri.Their open reading frame (ORF) encoded a polypeptide consisted of a signal peptide and a α2-macroglobulin domain, one or multi-number C 1q and carbohydrate recognition domain, and a fibrinogen-related domain, respectively.They displayed structural similarity to the mammalian complement components,including C3, C1q, MBL and ficolin.
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