We develop a multilevel atomic master equation approach and theoretically investigate real coherent dynamics of inner-shell electrons of a neon gas, irradiated by a high-intensity X-ray laser with a full temporal coherence.This method combines the processes of coherent dynamics induced by the X-ray laser and incoherent relaxations due to spontaneous and Auger decays.In contrast to the rate equation approach [1,2], we find that coherence can suppress the multiphoton absorptions of a neon gas in the ultra-intense X-ray pulse, due to coherence-induced Rabi oscillations and power broadening effects (as shown in the left panel of Fig.1).We study the influence of coherence on ionization processes of neon, and directly prove sequential single-photon processes for both outer-and inner-shell electrons dominate the ionizations for the recently typical experiments with a laser intensity of ≈ 101s W/cm2.We discuss possible experimental implementations such as signatures for coherent evolution of inner-shell electrons via resonance fluorescence processes (as shown in the right panel of Fig.1).