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肾透明细胞癌术后复发预测模型的建立
【机 构】
：
中国人民武装警察部队后勤学院附属医院泌尿外科,天津 天津医科大学第二医院泌尿外科,天津
【出 处】
：
泌尿生殖肿瘤华夏医学论坛2016暨长城国际泌尿男科转化医学论坛2016
【发表日期】
：
2016年8期
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从1989年作者成为硕博连读研究生，开展泌尿系统肿瘤基因研究至今已经整整26年了。作者在多位老师的悉心指导下，应用PCR及第二代测序技术，先后在小儿Wilms瘤、肾癌及膀胱癌等泌尿生殖系统肿瘤开展单基因、多基因及多组学研究；发现膀胱癌21个高频突变基因和8个染色质重塑基因，后者被Cell评论创立癌症发生的“染色质重塑-肿瘤抑制理论”；发现肾癌进化及转移新机制；发现膀胱癌突变频率最高的Driver基
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