老年女性严重骨质疏松有无骨折患者骨密度、骨转换指标和FRAX评估差异的研究

来源 :第七届国际骨质疏松及骨矿盐疾病学术会议 | 被引量 : 0次 | 上传用户：bellwang99

【摘要】

：

【作者】

：

曾雅琳胡世弟李鑫戴如春

【机构】

：

中南大学湘雅二医院内分泌科湘潭市第二人民医院内分泌科

【出处】

：

第七届国际骨质疏松及骨矿盐疾病学术会议

【发表日期】

：

2014年3期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

目的比较老年女性严重骨质疏松有无骨折患者骨密度(面积骨密度、体积骨密度),骨转换指标和FRAX评估骨折风险概率的不同,探讨二者之间存在的差异.方法根据我国骨质疏松诊断标准,横断面研究30例严重骨质疏松老年女性,其中骨折组与无骨折组各15例.进行问卷调查收集相关资料及基本情况筛查后,采用双能X线吸收仪(DXA)测量腰椎1～4及左髋部面积骨密度(aBMD)、单能定量CT(QCT)测量腰椎2～4及左髋部体积骨密度(vBMD);用ELISA法检测血清骨钙素(OC)、骨源性碱性磷酸酶(BAP)、抗酒石酸酸性磷酸酶(TRAP-5b)及尿Ⅰ型胶原交联C端顶端肽(UCTX);使用WHO推荐的骨折风险评估软件(FRAX)计算10年内骨质疏松引起的主要骨折及髋骨骨折概率.

其他文献

Ovariectomy-induced osteoporosis influences the middle and late periods of bone healing in a mouse f

Background: It is known that bone healing was delayed in the presence of osteoporosis in humans.However, due to the complexities of the healing of osteoporotic fractures, animal models may be more app

会议

Aromatase inhibitors associated musculoskeletal disorders and bone fractures in postmenopausal breas

Background: As the prognosis of early breast cancer patients improves, the long-term safety of aromatase inhibitors (AIs) is increasingly important.In the present study, we retrospectively investigate

会议

The influence of PPAR y gene silencing on the osteogenic and adipogenic differentiation of rat bone

Background: Peroxisome proliferator-activated receptor γ (PPAR γ), considered to be the master regulator, is both necessary and sufficient for adipogenesis.However, there are few reports regarding the

会议

Bone morphogenetic protein 9 stimulates fracture healing in osteoporotic rats

Background: Osteoporosis is a common disease characterised by a systemic impairment of bone mass and microarchitecture that significantly increases the incidence of fragility fractures.The aim of this

会议

Mi-Gu capsule improves bone fracture healing in a mouse model of osteoporosis: a micro-computed tomo

Background: Mi-Gu Capsule (MG) is the water extract of a Chinese herbal formula Bushenfang (BSF), which composed of Herba Epimedii, Radix Polygoni, Radix Astragali, Herba Dendrobii, Herba Cistanches,

会议

Repair of dog radial bone defects using true bone ceramics combined with BMP-2-related peptide

Background: Osteoporosis is a common disease among elderly people.Its main consequence is the increasing risk of bone fracture.Bone defects caused by osteoporotic fracture often require bone graft tre

会议

Synchronization of calcium sulphate cement degradation and new bone formation is improved by externa

Background: A major challenge faced in the bone materials of weight-bearing without internal fixture support is the mismatch of material degradation and new bone formation,leading to weakening or even

会议

Viability, proliferation, differentiation of preosteoblast MC3T3-E1 on three dimensional plottednHA/

Background: Osteoporotic fractures have the characteristic of diverse and irregular fracture shape, high incidence of delayed union and nonunion, with decreased bone formation and impaired microarchit

会议

Reinforcement of calcium phosphate cement using silk fibroin (SF) and self-assembled SF-hydroxyapati

Background: Vertebral augmentation has been widely used to treat vertebral compression fractures caused by osteoporosis, multiple myeloma, and osteolytic metastases.Biodegradable calcium phosphate cem

会议

The drug release speed and in vitro bioactivity of a novel three-dimensional graphene oxide scaffold

Background: The osteoporotic fractures are difficult to union, owing to the lack of bone formation, thus in clinic,osteogenic growth factors are urgently needed to facilitate the healing process.It ha

会议

老年女性严重骨质疏松有无骨折患者骨密度、骨转换指标和FRAX评估差异的研究

与本文相关的学术论文