【摘 要】
：
Objective:In order to evaluate protective Effect of different compatibility proportion of Aconiti Lateralis Radix Praeparata and Ginseng Radix et Rhizoma hypoxia injury in neonatal rats cardiomyocytes
【机 构】
：
Pharmacy College,Changchun University of Chinese Medicine,Changchun 130117,China
【出 处】
：
世界中医药学会联合会中药药理专业委员会第七届学术会议、全国中药药理联合会第二届学术年会暨第20届中日健康学术研讨会
论文部分内容阅读
Objective:In order to evaluate protective Effect of different compatibility proportion of Aconiti Lateralis Radix Praeparata and Ginseng Radix et Rhizoma hypoxia injury in neonatal rats cardiomyocytes.Method:The primary cultured cardiac muscle cells (6days) were randomly divided into NC group,OGD group,OGD+AG group,OGD +BS group.We established the injury model of primary neonatal rats cardiac muscle cell sugar anoxia / reoxygenation sugar,to survey the effect of different compatibility proportion of Aconiti Lateralis Radix Praeparata and Ginseng Radix et Rhizoma of medicated serum of spontaneous imp frequency,cell viability,superoxde dismutase (SOD),malondialdehyde (MDA),Nitric oxide (NO) and lactate dehydrogenase (LDH) in neonatal rat hypoxia injury cardiomyocytes.Result:Compared with model group,spontaneous imp frequency,cell viability,the activity of SOD were increased obviously,the content of MDA,the secretory volume of NO and the release rate of LDH were decreased obviously (P<0.05) in medication administration groups.After 48h of reoxygenation sugar,Compared with other medicated serum groups,spontaneous imp frequency,the cell viability,the activity of SOD were increased obviously,the content of MDA and the release rate of LDH were decreased obviously (P<0.05) in medicated serum (AG2∶1)group.Conclusion:There was a significant protective effect of different compatibility proportion of Aconiti Lateralis Radix Praeparata and Ginseng Radix et Rhizoma hypoxia injury in neonatal rats cardiomyocytes,the optimization compatibility proportion in AG2∶1.
其他文献
基层医疗卫生服务是政府实行一定福利政策的社会公益事业,基层医疗卫生服务的投入和对服务的补偿关系到基层医疗卫生服务的健康发展.2009年新一轮医改以来,围绕保基本、强基层、建机制,取得了重要进展,给基层医疗卫生机构的发展带来了机遇和挑战,本文从基层医疗卫生服务能力存在的问题及提高基层医疗卫生服务能力的财政政策思考两个方面入手,提出有效地强化基层医疗机构服务能力的财政政策,继续加大投入,推动医改向纵深
Systems biology has revealed that human cells and tissues are composed of complex,networked systems with redundant,convergent and divergent signalling pathways.Most human chronic diseases with a high
Aim of study:To examine the effects of active components of Radix Scrophulariae (ACRS) on ventricular remodeling in spontaneously hypertensive rats (SHR) and the underlying mechanism.Material and meth
Aim of study:Jiangzhi Capsule is a listed traditional Chinese medicine and has been used for abnormalities of lipid metabolism over ten years in Australia.To obtain better understanding Jiangzhi Capsu
Aim of the study:The study is to research the protective mechanisms of Compound Danshen Tablet (CDT) against myocardial ischemia/reperfusion (MI/R) injury via the Akt-eNOS signaling Pathway in rats.Ma
The paper,based on the previous publication as special impact of Chinese medicine theories on supramolcular chemistry,aims to analyze the natural origination for the Chinese medicine and to explain th
Aim of study:To investigate the alteration of contractile and relaxant responses of the isolated gastric smooth muscle in early diabetic rats,analyze the effects and mechanism of berberine on improvin
中药复方是中医理、法、方、药的重要组成部分,是临床防治疾病的主要形式.应用现代科学技术研究中药复方功效的配伍规律,作用特点与作用机制,阐释中药复方功效的科学内涵是中医药现代化发展的必然趋势,也是目前中药复方研究的难点与热点.中药复方功效的研究首先依据中药复方的功效与主治,从中医临床出发,将疾病中医证候的诊断标准、疗效评价技术与方法用于中药复方功效的研究;制备符合中医临床病证特征的动物模型,并进行中
Aim of study:Evaluate its reliability by counterevidence study on coronary heart disease with phlegm-stasis cementation syndrome induced by combing coronary artery balloon-injury with high-lipid diet
Aim of study:In the past,overeating was regarded as the main cause of increasing adiposity,but now a new viewpoint from JAMA suggested that energy metabolic defects may precede overeating in obesity.M