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Metarhizium robertsii has been used as a model to study fungal pathogenicity to insects.In this study,we systematically investigated MAPK cascade-mediated regulation of pathogenicity,conidiation and tolerance to abiotic stresses in M.robertsii.M.robertsii has complete Fus3-,Hog1-and Slt2-MAPK cascades and incomplete Ime2-MAPK cascade.