Multiple specific populations,including MSMs,IDUs,and FPDs,are involved in HIV epidemic in China.In recent years,HIV transmission due to heterosexual transmission also contributed greatly to HIV epide
Background To date,we still lack an ideal strategy for designing of envelope glycoprotein(Env)vaccines to elicit protective antibodies against HIV-1 infection.The mechanisms for the poor immunogenicit
The Human immunodeficiency virus type 1(HIV-1)fusion process is an important step for the development of drugs to prevent virus infection.Peptides corresponding to the N-(HR1)and C-terminal(HR2)heptad
Aim: To determine the effect of VIR576,a dimeric 20-mer peptide potently inhibits HIV-1 entry,on antigen-specific T cell and non-antigen-specific T cell activation.Methods: In vitro T-cell proliferati