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5. Adverse Outcome Pathway (AOP) for Propylene Oxide (PO)-Induced Rodent Nasal Tumors Driven by Sustain

Adverse Outcome Pathway (AOP) for Propylene Oxide (PO)-Induced Rodent Nasal Tumors Driven by Sustain

来源 :2015毒性测试替代方法与转化毒理学(国际)学术研讨会 | 被引量 : 0次 | 上传用户：a294953312

【摘 要】

：

AOPs provide an understanding of how chemicals induce adverse effects in biological systems through their toxicity pathways and modes of action.Development of an AOP for the weakly genotoxic PO induci

【作 者】

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Renjun Gao Joanna Klapacz Lynn Pottenger Robert Budinsky 

【机 构】

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Dow Chemical (China) Investment Company Limited, Beijing 100738, China

【出 处】

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2015毒性测试替代方法与转化毒理学(国际)学术研讨会

【发表日期】

：

2015年5期

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AOPs provide an understanding of how chemicals induce adverse effects in biological systems through their toxicity pathways and modes of action.Development of an AOP for the weakly genotoxic PO inducing site-of-contact, nasal tumors via non-genotoxic effects has been accepted by OECD EAG in June 2014.

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