【摘 要】
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Lipopolysaccharide-induced TNF-α factor (LITAF), which participates in innate immune response and regulates TNF-α transcription, has been identified and characterized in various organisms.In a study t
【机 构】
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National pathogen collection center for aquatic animals, Shanghai Ocean University, 201306 Shanghai,
【出 处】
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2013年中国水产学会鱼病专业委员会学术研讨会
论文部分内容阅读
Lipopolysaccharide-induced TNF-α factor (LITAF), which participates in innate immune response and regulates TNF-α transcription, has been identified and characterized in various organisms.In a study to screen interacting cellular proteins with grass carp reovirus using yeast two-hybrid system, a grass carp homologue of LITAF was identified to bind the NS26 protein encoded by the S 11 genomic fragment of Grass carp reovirus (GCRV).In this study, grass carp LPS-induced TNF-α factor gene (designated as CiLITAF) was cloned and sequenced from the cDNA library constructed for the yeast two-hybrid screening.
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