【摘 要】
:
Protein microarrays have been employed to screen tens to thousands of proteins simultaneously for the observation of the biochemical activities in the prote
【机 构】
:
NationalTsing-HuaUniversityTaiwan
【出 处】
:
2008中国深圳蛋白质和多肽科学大会
论文部分内容阅读
Protein microarrays have been employed to screen tens to thousands of proteins simultaneously for the observation of the biochemical activities in the protein-protein,protein-nucleic acid and small molecule interactions.This technology allows high throughput analysis and holds great potential for basic molecular biology research,disease marker identification,toxicological response profiling and pharmaceutical target screening.However,proteins easily malfunction in harsh environments so that they are hardly preserved before the application because of their complex and fragile structures.On the other hand,identify scarce amount of proteins less than fM range is very important and challenge for disease diagnosis at very early stage.
其他文献
Interactome research has shown that proteins participate in a wide number and variety of interactions.Together,these form networks of great complexity.Howev
Sixty years ago,we had a very primitive view of proteins in terms of ellipsoidal models obtained from studies of the hydrodynamic properties of protein solu
Collagen serves as a structural scaffold and a barrier between tissues,and thus collagen catabolism (collagenolysis) is required to be a tightly regulated p
The separation and analysis of nucleic acids and proteins using gel electrophoresis and membrane transfer is a longtime cornerstone of molecular biology res
The biopharmaceutical industry has,by all measures,been a tremendous success,in terms of both human health and economics.The application of vaccines has pra