全真一气汤总多糖对免疫抑制小鼠肠道sIgA的影响及其机制研究

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目的1.探讨全真一气汤总多糖对肠道黏膜的免疫调节作用。2.研究全真一气汤总多糖的免疫药理机制,定位其作用的靶器官或靶点,以及分子机制。方法取健康SPF级KM小鼠24只,雌雄各半,6~8周龄,体重18~22g,按体重随机分为正常对照组,模型组,全真一气汤总多糖组(QZYQPS),每组8只,QZYQPS组每天灌胃给予全真一气汤总多糖,剂量为1g·kg~(-1)·d~(-1),前两组灌胃给予与多糖同体积的生理盐水,共8d,在实验的第7天给模型组、QZYQPS组小鼠腹腔注射环
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