脑出血急性期中西医结合优化治疗方案临床研究

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Objective:Through the cooperation of T. C. M. and Western medicine optimizationplan (Hereafter refers to as Zhongfengxingnao oral liquid plan) and the doctor practicing western medicine therapeutic schedule treatment acute cerebral hemorrhage’s clinical contrast research, to evaluate the validity and security of Zhongfengxingnao oral liquid plan.Methods:AICH patients from affiliated hospital of CDUTCM during January 2006 to January 2009 were included for retrospective case-control study. They were from two groups Zhongfengxingnao group with 31 cases (given Zhongfengxingnao oral liquid’25ml qid plus basic western medicine therapy), Control group (given basic western medicine therapy). Effect Determination:(1) mortality, (2) hematoma absorptivity, (3)modified Rankin Scale, National Institutes of Health Stroke Scale, Barthel Index. Baseline information on the two groups was compared, the effection of 14days,28days and 90days was evaluated, as well as possible adverse reactions were recorded. Evaluation-was performed with software SPSS 13.0. Date that death and loss patients in the most recent before death or loss was involved to statistics.Results:(1)Baseline evaluation:the baseline conditions in two groups were comparable, P>0.05. (2) Comparison two groups absorption of hematoma were no significant difference after 28days treatment, P>0.05. (3) Zhongfengxingnao group effect on improving T. C. M. symptoms and signs, as well as improving T. C. M. symptoms and signs impact on daily life was better than Control group after 28days treatment, P<0.05. (4) Comparison two groups modified Rankin Scale (mRS) and National Institutes of Health Stroke Scale (NIHSS) were no significant difference in 14days and 28days treatment, P>0.05. Comparison two groups modified Rankin Scale (mRS) 90days latter was no significant difference, P>0.05, but comparison two groups NIHSS 90days latter was significant difference P<0.05. (5) Comparison two groups percentage of patients modified Rankin Scale (mRS) less than or equal to 2 were no significant difference after 28days treatment and 90days later, P>0.05. Comparison two groups percentage of patients Barthel Index (BI) greater than or equal to 60 were no significant difference after 28days treatment and 90days later, P>0.05. (6) Two groups had no serious adverse reactions.Conclusion:Compared with western medicine, optimized integration of T. C. M. and western medicine had considerable effect on mortality, hematoma absorptivity, improving the quality of life and improving neurological deficit after 14day&28day treatment but had obvious advantages on improving neurological deficit 90 latter. Compared with western medicine, optimized integration of T. C. M. and western medicine had obvious advantages on improving T. C. M. symptoms, T. C. M. symptoms and signs impact on daily life. Optimized integration of T. C. M. and western medicine had advantage trends on improving neurological deficit and quality of life. Zhongfengxingnao program is the best option with facilitate and exact effect on treating the acute cerebral hemorrhage.
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