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目的:研究分析硫辛酸治疗糖尿病周围神经病变90例的临床效果。方法:选取在我院接受治疗的90例糖尿病周围神经病变患者进行研究。随机分为观察组和对照组,各45例患者。给予观察组患者静脉滴注600mg硫辛酸混合250ml生理盐水治疗;给予对照组静脉滴注500μg甲钴胺混合100ml生理盐水治疗。结果:观察组的总有效率明显高于对照组,两组患者接受治疗后,神经传导速度均增加,对照组治疗前后组内比较无明显差异(P>0.05),观察组治疗前后组内对比存在显著性差异(P<0.01),观察组治疗后的神经传导速度改善情况优于对照组患者,组间比较存在显著差异(P<0.01)。结论:硫辛酸治疗糖尿病周围神经病变的临床疗效显著,可以推广至临床应用。
Objective: To study the clinical effect of lipoic acid in treating 90 cases of diabetic peripheral neuropathy. Methods: Ninety patients with diabetic peripheral neuropathy treated in our hospital were selected for study. Randomly divided into observation group and control group, each of 45 patients. Patients in the observation group were given intravenous infusion of 600mg lipoic acid and 250ml normal saline. The control group was given 500μg mecobalamin and 100ml normal saline intravenously. Results: The total effective rate in the observation group was significantly higher than that in the control group. The nerve conduction velocity increased after treatment in both groups, but there was no significant difference between before and after treatment in the control group (P> 0.05) There was a significant difference (P <0.01). The improvement of nerve conduction velocity in the observation group was better than that in the control group, there was significant difference between the two groups (P <0.01). Conclusion: The clinical efficacy of lipoic acid in the treatment of diabetic peripheral neuropathy is significant and can be extended to clinical application.