本文介绍35例应用自然避孕法的妇女,在月经周期的不同时期,观察记录宫颈粘液,尿中雌、孕激素及阴道上皮细胞的核致密指数(KPI),嗜酸性指数(EI)的相关变化。结果表明:1.在卵泡期至排卵前,宫颈粘液量逐日增多,呈稀薄、透明、滑润、拉丝度大的特点。阴道上皮细胞的KPI 和EI 与宫颈粘液一样和雌激素水平呈正相关。2.排卵后,黄体期宫颈粘液量、性状、阴道上皮细胞的KPI 和EI 与孕激素水平呈负相关。本文示宫颈粘液、阴道上皮细胞的KPI 和EI 受卵巢激素的调节,具有特定的变化规律。 In this paper, 35 women with natural contraception were enrolled in this study. During the menstrual cycle, the changes of nuclear densification index (KPI) and eosinophilic index (EI) in cervical mucus, urine estrogen, progesterone and vaginal epithelial cells were observed and recorded . The results showed that: 1. In the follicular phase to ovulation before, cervical mucus increased day by day, was thin, transparent, smooth, drawing a large degree of characteristics. Vaginal epithelial cells KPI and EI and cervical mucus and estrogen levels were positively correlated. 2. After ovulation, luteal phase of cervical mucus volume, traits, vaginal epithelial cells KPI and EI and progesterone levels were negatively correlated. This article shows cervical mucus, vaginal epithelial cells KPI and EI regulation by ovarian hormones, with a specific variation.