论文部分内容阅读
目的研究手术和放射治疗喉癌对病人甲状腺功能和营养状况的影响。方法基于“知情同意”的原则,从确诊的喉癌病人中,根据其治疗方案,选择将接受手术治疗加放射治疗的病人(以下称放疗病人)24例(观察组),和将只接受手术治疗的病人(以下称手术病人)24例(对照组)。要求被选择的病人没有合并其他临床严重疾病。全部病人手术后全部采用管饲营养支持。结果观察组和对照组的血清TSH水平升高,伴有T3、T4水平降低,两组有显著性差异(P<0.01)。营养状况观察组和对照组两组无显著性差异(P>0.05)。结论手术后喉癌病人的甲状腺功能无明显变化而放射治疗后出现甲状腺功能减低。
Objective To study the effects of surgery and radiotherapy on thyroid function and nutritional status in patients with laryngeal cancer. Methods Based on the principle of “informed consent”, 24 patients (observation group) who underwent surgical treatment plus radiotherapy (hereinafter referred to as radiotherapy) were selected from among the confirmed patients with laryngeal cancer according to their treatment plan, and only Twenty-four patients (control group) underwent surgical treatment (hereinafter referred to as surgical patients). The patients selected are not required to incorporate other clinically serious illnesses. All patients after surgery using tube feeding nutrition support. Results The level of serum TSH in the observation group and the control group increased with the decrease of T3 and T4 levels. There was a significant difference between the two groups (P <0.01). There was no significant difference between nutritional status observation group and control group (P> 0.05). Conclusions Thyroid function in patients with laryngeal cancer after operation has no obvious change and thyroid function decrease after radiotherapy.