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目的分析急性脑梗死患者颅内动脉狭窄的危险因素,并提出对策防治该病。方法对医院2014年9月-2015年10月收治的急性脑梗死患者120例行数字减影脑血管造影术,判断颅内动脉狭窄的特征,将其分为狭窄组62例和非狭窄组58例,比较2组患者的糖尿病、高血压、冠心病、饮酒史、吸烟史、血尿酸和血脂情况及水平。结果动脉血管狭窄组总胆固醇水平、低密度脂蛋白胆固醇水平均明显高于无狭窄组患者;Pearson相关数据分析表明,颅内动脉峡窄与糖尿病史、高血压史、冠心病、饮酒史、吸烟史、总胆固醇、血尿酸、低密度脂蛋白胆固醇相关;Logistic回归分析结果表明,糖尿病史、高血压史、冠心病及以上因素均为急性脑梗死患者颅内动脉狭窄的危险因素。结论除了糖尿病及高血压,血尿酸及血脂指标也是造成脑梗死患者颅内血管狭窄的危险因素。
Objective To analyze the risk factors of intracranial arterial stenosis in patients with acute cerebral infarction and to put forward countermeasures to prevent and cure the disease. Methods Digital subtraction angiography was performed on 120 patients with acute cerebral infarction admitted to the hospital from September 2014 to October 2015. The characteristics of intracranial arterial stenosis were determined and divided into 62 cases of stenosis group and 58 cases of non-stenosis group Cases, comparison of two groups of patients with diabetes, hypertension, coronary heart disease, alcohol consumption history, smoking history, serum uric acid and lipid status and level. Results The levels of total cholesterol and low density lipoprotein cholesterol in arterial stenosis group were significantly higher than those in non-stenosis group. Pearson correlation analysis showed that intracranial artery narrowing and diabetes mellitus, history of hypertension, coronary heart disease, alcohol drinking history, smoking history History, total cholesterol, serum uric acid, and low density lipoprotein cholesterol. Logistic regression analysis showed that diabetes mellitus, history of hypertension, coronary heart disease and above were the risk factors for intracranial arterial stenosis in patients with acute cerebral infarction. Conclusion In addition to diabetes and high blood pressure, serum uric acid and lipids are also risk factors for intracranial vascular stenosis in patients with cerebral infarction.