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目的 研究中药育精阴治疗免疫性不育的作用及其机理。方法 运用主动免疫法造成豚鼠实验性变态反应性睾丸炎 (EAO)模型 ,观察睾丸生精细胞和附睾尾部精子质量的变化。运用不同剂量育精阴灌胃 ,观察育精阴对生精上皮和附睾尾部精子质量的作用。结果 发现实验性变态反应性睾丸炎造成睾丸生精细胞退行性病变 ,附睾精子质量下降。育精阴可减轻和修复实验性变态反应对睾丸附睾的损伤 ,提高附睾精子质量。结论 育精阴对实验性变态反应性睾丸炎造成的免疫损伤有修复作用
Objective To study the effect and mechanism of yinjing yin yin on immune sterility. Methods The model of experimental allergic orchitis (EAO) was induced by active immunization in guinea pigs. The changes of spermatogenic cells and epididymal tail were observed. Using different doses of yin yang stomach, observe yinjing on spermatogenic epithelium and epididymis tail sperm quality. The results showed that experimental allergic orchitis caused by testicular germ cell degeneration, decreased sperm quality of the epididymis. Yuening Yin can reduce and repair experimental allergic reaction to the damage of the testicular epididymis and improve the sperm quality of the epididymis. Conclusion YoYing Yin can repair the immune damage induced by experimental allergic orchitis