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[目的]探讨染色体多态性与生育异常临床效应之间的关系。[方法]以有异常生育史的个体作为患者组,无异常生育史的正常个体作为正常对照组,通过培养外周血淋巴细胞、常规染色体制备、G显带技术进行核型分析,判断两组中各种染色体多态性的检出率有无差异。[结果]患者组染色体多态性的检出率高于正常组,但两组间染色体多态性检出率的差异不具有统计学意义。[结论]尚不能认为染色体多态性与个体异常生育史之间有必然的联系。
[Objective] To investigate the relationship between chromosomal polymorphism and the clinical effect of abnormal fertility. [Methods] The individuals with abnormal fertility history as the patient group and the normal individuals without abnormal birth history as the normal control group. The karyotypes were analyzed by culturing peripheral blood lymphocytes, routine chromosome preparation and G-banding technique, There is no difference in the detection rate of various chromosome polymorphisms. [Results] The detection rate of chromosome polymorphism in patients was higher than that of normal group, but the difference of the detection rate of chromosome polymorphism between the two groups was not statistically significant. [Conclusion] The relationship between chromosome polymorphism and abnormal birth history can not be considered yet.