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目的了解鹤壁市儿科感染性疾病抗生素的使用情况,为指导抗生素合理使用提供参考依据。方法随机抽取2006～2009年鹤壁市鹤煤总医院(二级甲等医院)儿科因感染性疾病住院病例700例,调查抗生素联合使用情况、药品种类、使用频率、平均用药天数,分析抗生素使用与药敏试验和白细胞(WBC)计数的关系。结果2006～2009年,鹤壁市儿科感染性疾病抗生素的使用率分别为95%,100%,99%,100%;各年使用频率最高的抗生素分别为头孢呋辛(37%)、头孢呋辛(32%)、头孢硫咪(25%)、头孢硫咪(33%);平均用药天数最多的抗生素分别为头孢呋辛(4～5 d)、头孢呋辛(4～5 d)、头孢噻肟/舒巴坦(4～7 d)、头孢噻肟/舒巴坦(6～7 d);药敏试验率分别为3.16%,4%,2.53%,3%;WBC计数在正常范围内(4×109/L～10×109/L)的抗生素使用率分别为54.2%,63%,67.7%,71%。结论鹤壁市儿科感染性疾病抗生素用药单一,缺乏科学依据,抗生素使用需进一步规范。
Objective To understand the use of antibiotics in pediatric infectious diseases in Hebi City and provide a reference for guiding the rational use of antibiotics. Methods A total of 700 hospitalized cases of pediatric infectious diseases in Hebi Coal General Hospital of Hebi City from 2006 to 2009 were randomly selected. The antibiotic combination, the type of drugs, the frequency of use and the average medication days were investigated. The antibiotic use and Susceptibility testing and white blood cell (WBC) count relationship. Results From 2006 to 2009, the prevalence rates of antibiotics in pediatric infectious diseases in Hebi City were 95%, 100%, 99% and 100% respectively. The antibiotics with the highest frequency of use were cefuroxime (37%), cefuroxime (32%), cefathiamil (25%) and cefathiamid (33%). The antibiotics with the highest average number of days were cefuroxime (4-5 d), cefuroxime (4 ~ 7 d) and cefotaxime / sulbactam (6 ~ 7 d). The susceptibility test rates were 3.16%, 4%, 2.53% and 3% respectively. The WBC count was in the normal range The antibiotic utilization rates within the range of 4 × 109 / L to 10 × 109 / L were 54.2%, 63%, 67.7% and 71%, respectively. Conclusion Hebi City pediatric infectious diseases antibiotics single, lack of scientific basis, the use of antibiotics need to be further standardized.