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为探讨我国乙型肝炎（乙肝）和肝癌高发区乙肝疫苗的免疫效果，在广西隆安县对儿童和新生儿实施乙肝疫苗大规模免疫。免疫后１０年，于１９９５年对１～３９岁人群进行了调查，并用ＲＩＡ法检测了乙肝ＨＢｓＡｇ、抗－ＨＢｓ和抗－ＨＢｃ。结果表明，１～３９岁自然人群中乙型肝炎疫苗接种率为４２．４％；ＨＢｓＡｇ阳性率为９．５％，其中７～９岁的ＨＢｓＡｇ年龄高峰已消失，尤其在１～８岁人群下降了１００．０％～８３．０％，人群的抗－ＨＢｓ阳性率１～２岁组婴幼儿最高，为８５．５％，以后随年龄增长而逐步下降，在１～１９岁人群中，抗体阳性率显著高于１９８５年的相同年龄组。表明儿童大规模免疫后，紧接着实行新生儿逐年进行计划免疫，是加速控制乙肝感染的有效措施。
To investigate the hepatitis B (hepatitis B) and hepatitis B high incidence of hepatitis B vaccine immunization in Guangxi Longan County of children and newborns to implement large-scale immunization of hepatitis B vaccine. After 10 years of immunization, in 1995, a survey was conducted on the 1-39-year-old population and HBsAg, anti-HBs and anti-HBc were detected by RIA. The results showed that the hepatitis B vaccination rate was 42.4% in the natural population from 1 to 39 years old and the positive rate of HBsAg was 9.5%. The peak age of HBsAg in 7-9 years old had disappeared, especially in the population aged 1-8 years Decreased by 100.0% -83.0%. The positive rate of anti-HBs in the population was the highest (85.5%) in infants aged 1 ~ 2 years old and then decreased gradually with age. In the age group of 1 ~ 19 years old, The positive rate of antibody was significantly higher than the same age group in 1985. After the large-scale immunization of children, the planned immunization followed by newborns is an effective measure to speed up the control of hepatitis B infection.