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目的比较麻醉和镇静术对接受结肠镜检查患者的安全性及治疗效果。方法 225例于我院行结肠镜检查的患者,随机接受丙泊酚伍用芬太尼麻醉或咪唑安定清醒镇静诊疗,比较两组患者结肠镜检查过程中血压、心率、血氧饱和度变化情况及呻吟、肢动等不良反应,并追踪观察患者术后清醒时间及不良事件的发生率。结果麻醉组患者呻吟、肢动发生率显著低于清醒镇静组;清醒镇静组血压、心率、血氧饱和度下降显著低于麻醉组。两组患者给药时间、术中及术后不良事件的发生率无显著差异。结论麻醉及清醒镇静术均可有效缓解结肠镜检查所致的不良反应,无严重不良事件发生。
Objective To compare the safety and efficacy of anesthesia and sedation in patients undergoing colonoscopy. Methods A total of 225 patients undergoing colonoscopy in our hospital were randomized to receive propofol anesthesia or conscious sedation with midazolam. The changes in blood pressure, heart rate, blood oxygen saturation, and moan during the colonoscopy were compared between the two groups , Limbs and other adverse reactions, and follow-up observation of patients with postoperative wake-up time and the incidence of adverse events. Results Patients in the anesthesia group moaned and the incidence of limb movements was significantly lower than that of conscious sedation group. The decline of blood pressure, heart rate and oxygen saturation in conscious sedation group was significantly lower than that of anesthesia group. The two groups of patients administered time, intraoperative and postoperative adverse events no significant difference in the incidence. Conclusion Anesthesia and conscious sedation can effectively relieve the adverse reactions caused by colonoscopy without serious adverse events.