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目的分析住院急性呼吸道感染(ARI)患儿病毒病原检测结果,为临床儿童急性呼吸道感染提供病毒病原学诊断依据。方法选择2003年4月至2005年3月重庆医科大学儿童医院呼吸内科住院治疗的急性呼吸道感染患儿,取其鼻咽分泌物做免疫荧光检测筛查7种常见呼吸道病毒抗原,包括呼吸道合胞病毒(RSV)、腺病毒、流感病毒A及B型、副流感病毒Ⅰ、Ⅱ、Ⅲ型,对检测标本阳性的病例进行统计分析。结果1052份标本中,阳性标本409份,占38.88%。其中RSV阳性标本360份,占总阳性标本例数的88.02%,副流感病毒Ⅲ37份占9.05%;RSV发病高峰时期在12月至次年2月和7、8月两个时期;RSV感染多见于3岁以下,发病高峰年龄为2～6个月,男女发病比例为2.24∶1。结论2003～2005年重庆地区急性呼吸道感染的病毒病原体仍以RSV为主。
Objective To analyze the results of virus pathogen detection in children with acute respiratory infection (ARI) in hospital and provide the basis of virus etiological diagnosis for clinical children with acute respiratory infection. Methods From April 2003 to March 2005, Chongqing Children’s Hospital of Chongqing Medical College Respiratory Medicine hospitalized children with acute respiratory tract infection, nasopharyngeal secretions taken for immunofluorescence screening of seven common respiratory virus antigens, including respiratory syncytial Virus (RSV), adenovirus, influenza virus A and B, parainfluenza virus type Ⅰ, Ⅱ, Ⅲ, the positive samples were tested for statistical analysis. Results Of 1052 specimens, 409 specimens were positive, accounting for 38.88%. Among them, 360 were positive for RSV, accounting for 88.02% of the total positive samples and 9.05% for parainfluenza virus Ⅲ37. The peak period of RSV was between December and February and July and August. RSV infection was more Seen below 3 years of age, the peak incidence age of 2 to 6 months, the incidence of male to female ratio of 2.24: 1. Conclusion The virus pathogens of acute respiratory infection in Chongqing from 2003 to 2005 were still mainly RSV.