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目的:探讨喜炎平联合阿昔洛韦治疗小儿手足口疾病的临床疗效。方法:将88例手足口病患儿随机分成两组,一组使用喜炎平联合阿昔洛韦注射液,为治疗组(48例),另一组单用阿昔洛韦注射液,为对照组(40例),对两组的临床症状、体征变化及改善时间进行观察和分析。结果:治疗组的临床症状及体征均较对照组消失早(P<0.01),改善时间少于对照组,用喜炎平联合阿昔洛韦注射液的治疗组总有效率为89.6%,用阿昔洛韦的对照组总有效率为77.5%,差异具有显著统计学意义(P<0.01)。结论:喜炎平联合阿昔洛韦注射液治疗小儿手足口病疗程短,见效快,无副作用。
Objective: To investigate the clinical efficacy of Xiyanping combined with acyclovir in the treatment of hand-foot-mouth disease in children. Methods: 88 cases of hand-foot-mouth disease were randomly divided into two groups. One group used Xiyanping combined with acyclovir injection for the treatment group (48 cases). The other group used acyclovir injection as The control group (40 cases), the clinical symptoms and signs of the two groups were observed and analyzed. Results: The clinical symptoms and signs of the treatment group disappeared earlier than the control group (P <0.01), and the improvement time was less than that of the control group. The total effective rate of the treatment group treated with Xiyanping combined with acyclovir injection was 89.6% The total effective rate of acyclovir control group was 77.5%, the difference was statistically significant (P <0.01). Conclusion: Xiyanping injection of acyclovir in children with HFMD treatment short, quick, no side effects.