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慢性乙型肝炎的发病机理与免疫应答和免疫调节功能紊乱有关。有研究表明乙型肝炎患者IL—2的产生及其活性均明显降低。外周血单个核细胞经PHA刺激后,其表面白细胞间索Ⅱ受体(IL—2R)表达能力亦明显下降。IL—2具有广泛的免疫调节作用。干抗素(IFN)虽为治疗乙型肝炎的有希望药物,可单独应用效果并不满意。经研究提出IFN与其它细胞因子联合使用可提高其疗效。我们采用纯化天
The pathogenesis of chronic hepatitis B and immune response and immune dysfunction related. Studies have shown that patients with hepatitis B IL-2 production and activity were significantly lower. Peripheral blood mononuclear cells stimulated by PHA, the surface of leukocyte intercellular cord receptor (IL-2R) expression was also significantly decreased. IL-2 has a wide range of immunomodulatory effects. Although anti-interferon (IFN) is a promising drug for the treatment of hepatitis B, it can not be applied alone. The study suggested that IFN in combination with other cytokines can improve its efficacy. We use purified day