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抗肿瘤药物研究策略 近年来抗肿瘤药物发展迅速,其研究经过几十年的历程已发展到一个新的阶段,杀伤型细胞毒药物的发展策略已转向针对新靶点,提高选择性,针对实体瘤、克服肿瘤耐药、寻找新型的化学结构和新的作用机理的药物研究,寻找新型抗肿瘤药的观念较新,技术及方法也在总结经验的基础上不断改进,新一代的针对特定肿瘤、特定靶点的高度自动化的高通量筛选方法正在建立并不断完善。新品种不断出现,对肿瘤治疗起到了积极的推动作用。
Antitumor drug research strategy In recent years, the rapid development of anticancer drugs, the study after decades of course has been developed to a new stage, the development of anti-cytotoxics strategy has been shifted to target new targets to improve selectivity, targeting entities Tumor, drug resistance to overcome tumor resistance, looking for new chemical structure and new mechanism of drug research, looking for a new concept of new anti-tumor drugs, technology and methods are also based on the experience of continuous improvement, a new generation of specific tumor Highly automated, high-throughput screening of specific targets is under way and is being refined. Emerging new varieties continue to play a positive role in promoting cancer treatment.