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目的:探讨慢性阻塞性肺疾病急性期(AECOPD)合并Ⅱ型呼吸衰竭患者行双水平无创正压通气治疗的效果。方法:选取我院2009年1月-2010年6月接收的AECOPD合并Ⅱ型呼吸衰竭患者56例,随机分别为对照组与观察组,每组28例,给予对照组患者常规治疗,观察组在对照组的基础上施加BiPAP治疗,观察两组患者治疗前后的血气变化,进而评判治疗效果。结果:两组患者经治疗后,对照组治疗有效率为71.43%,观察组为89.29%,组间比较差异显著(P<0.05);治疗后PaCO2、PaO2较之于治疗前均有明显改善,且观察组明显优于对照组,组间比较差异显著(P<0.05);对照组心率与呼吸频率不及观察组(P<0.05);两组患者血压比较无显著差异(P>0.05)。结论:AECOPD合并Ⅱ型呼吸衰竭患者行BiPAP治疗效果显著,值得推广。
Objective: To investigate the effect of double-level noninvasive positive pressure ventilation in patients with acute obstructive pulmonary disease (AECOPD) and type Ⅱ respiratory failure. Methods: Fifty-six patients with AECOPD type Ⅱ respiratory failure received in our hospital from January 2009 to June 2010 were randomly divided into the control group and the observation group, with 28 cases in each group. The patients in the control group were treated routinely. The control group based on the application of BiPAP treatment, the two groups were observed before and after treatment of blood gas changes, and then evaluate the therapeutic effect. Results: After treatment, the effective rate of the control group was 71.43%, the observation group was 89.29%, the difference was significant (P <0.05); after treatment PaCO2, PaO2 compared with before treatment were significantly improved, (P <0.05). The heart rate and respiratory rate in the control group were lower than those in the observation group (P <0.05). There was no significant difference in blood pressure between the two groups (P> 0.05). Conclusion: AECOPD with type Ⅱ respiratory failure in patients with BiPAP treatment is significant, it is worth promoting.