目的 :评估连续性肾脏替代疗法 (CRRT)在救治老年多器官功能衰竭 (MOFE)患者中作用。方法 :对我院应用CRRT救治 2 7例MOFE患者作回顾分析 ,并对CRRT的血管通路、装置、治疗方法及抗凝剂的使用等方面作了改进。结果 :改进方法后 ,血管通路以颈内静脉单针双腔导管为主 ;治疗时间改在白天 8～ 12时、血流量 10 0～ 2 0 0ml/min ;根据病情设定的超滤量 ;调整抗凝剂的应用等 ,使MOFE患者救治成功率提高 (改进前 2 5 % ,改进后 73.6 % )。结论 :CRRT是MOFE伴有急性肾功能衰竭的首选方法。CRRT可以改善MOFE患者的预后 PURPOSE: To evaluate the role of continuous renal replacement therapy (CRRT) in the treatment of elderly multiple organ failure (MOFE). Methods: 27 CRFT patients treated with CRRT were retrospectively analyzed. The vascular access, devices, treatment methods and anticoagulant use of CRRT were also improved. Results: After improving the method, the main access to the vascular access was internal jugular vein with single needle and double lumen catheter. The treatment time was changed from day 8 to day 12 with a blood flow of 100 ml to 200 ml / min. The ultrafiltration volume was set according to the condition. Adjusting the application of anticoagulants and so on, so that the success rate of treatment of patients with MOFE increased (improvement of 25%, improved 73.6%). Conclusion: CRRT is the first choice of MOFE with acute renal failure. CRRT can improve the prognosis of patients with MOFE