卡前列素氨丁三醇联合Bakri子宫填塞球囊导管治疗前置胎盘剖宫产产后出血的疗效观察

来源 :中国药物经济学 | 被引量 : 0次 | 上传用户:zy15400444
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目的探讨卡前列素氨丁三醇联合Bakri子宫填塞球囊导管治疗前置胎盘剖宫产产后出血患者的疗效。方法选取2015年3月至2017年3月于广东省佛山市顺德区妇幼保健院产科剖宫产分娩的前置胎盘产后出血患者50例作为研究对象,按随机数字表法将其分为观察组与对照组,各25例。对照组患者采用卡前列素氨丁三醇注射液治疗,观察组患者则在对照组治疗方案上联合应用Bakri子宫填塞球囊导管治疗,比较两组患者的治疗效果及相关临床指标。结果观察组患者治疗总有效率明显高于对照组,并且术中、术后2~24 h出血量及总出血量均明显少于对照组,差异均有统计学意义(均P<0.05);观察组患者手术用时明显短于对照组,差异有统计学意义(P<0.05),但两组患者恶露持续时间、外周血白细胞计数差异均无统计学意义(均P>0.05)。结论采用卡前列素氨丁三醇联合Bakri子宫填塞球囊导管治疗前置胎盘剖宫产产后出血疗效较单纯应用卡前列素氨丁三醇更为理想,止血速度更快,安全性理想。 Objective To investigate the curative effect of carboprost trometamol combined with Bakri womb balloon catheter in the treatment of pre-placental cesarean section postpartum hemorrhage. Methods From March 2015 to March 2017, 50 cases of antenatal placental hemorrhage with cesarean delivery in Shunde District Maternity and Child Care Hospital of Foshan City, Guangdong Province were selected as the research object. According to the random number table method, they were divided into observation group Compared with the control group, 25 cases each. The patients in the control group were treated with carboprost trometamol injection. The patients in the observation group were treated with Bakri intrauterine balloon catheter in combination with the control group. The therapeutic effect and related clinical indexes were compared between the two groups. Results The total effective rate of observation group was significantly higher than that of control group. The intraoperative and postoperative 2 ~ 24 h blood loss and total blood loss were significantly less than those in control group (all P <0.05). The operation time of the observation group was significantly shorter than that of the control group, the difference was statistically significant (P <0.05). However, there was no significant difference between the two groups in the duration of lochia and the peripheral blood leukocyte count (all P> 0.05). Conclusions The treatment of pre-placental cesarean section with carboprost trometamol combined with Bakri womb balloon catheter is better than carboprutin alone in the treatment of postpartum hemorrhage. The hemostasis is faster and the safety is better.
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