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结核病是我国重点控制的四大传染病之一,也是全球最主要的传染性疾病之一~[1]。我国是全球第二大结核病高负担国家,结核病疫情虽有所下降,但是结核病负担仍十分严重~[2]。抗结核药物是治疗结核病的根本途径,能否顺利进行抗结核药物的使用决定治疗的成败。但抗结核药物的不良反应严重,最常受累的器官是胃肠道系统(28.9%)和肝胆系统(23.7%)~[3]。抗结核药物的
Tuberculosis is one of the four major infectious diseases controlled by our country and one of the most important infectious diseases in the world [1]. China is the second-largest country with a high burden of tuberculosis in the world. Although the epidemic rate of tuberculosis has dropped, the burden of tuberculosis is still very serious. [2] Antituberculosis drugs are the fundamental way to treat tuberculosis. The success or failure of successful antituberculosis drug treatment depends on the success or failure of antituberculosis drugs. However, adverse reactions to anti-TB drugs are serious. The most commonly affected organs are the gastrointestinal system (28.9%) and hepatobiliary system (23.7%). [3] Anti-TB drugs