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目的研究高龄高危女性急性非ST段抬高型心肌梗死患者早期侵入治疗与保守治疗对患者预后的影响。方法入选新乡市中心医院心内科年龄>75岁,确诊为急性非ST段抬高型心肌梗死的女性患者,评分高危。随机分为A组(介入治疗组)、B组(保守治疗组),记录住院期间、发病后6个月、发病后1年主要心血管不良事件(包括死亡、心衰、缺血再住院、恶性心律失常)及出血等资料。结果与介入治疗组相比,住院期间保守组再发心绞痛率、心力衰竭率高,差异有统计学意义(P<0.05),保守组6个月内缺血再住院率、恶性心律失常、心力衰、死亡发生率都较介入治疗组高,差异有统计学意义(P<0.05),出血率二组对比差异无统计学意义(P>0.05),二组1年内缺血再住院率、恶性心律失常、心力衰竭、死亡发生率对比,保守组均高于介入治疗组,差异有统计学意义(P<0.05),出血率二组对比差异无统计学意义(P>0.05)。结论在高龄高危女性NSTEMI患者的治疗中,早期侵入性治疗是安全、有效的。
Objective To study the impact of early invasive treatment and conservative treatment on the prognosis of elderly patients with high-risk women with acute non-ST-segment elevation myocardial infarction. Methods A total of 75 female patients with acute non ST-segment elevation myocardial infarction who were admitted to Xinxiang Central Hospital were enrolled in this study. Patients were randomly divided into group A (intervention group) and group B (conservative treatment group). During hospitalization, 6 months after onset and 1 year after onset of major adverse cardiovascular events (including death, heart failure, Malignant arrhythmia) and bleeding and other information. Results Compared with the intervention group, the rates of recurrent angina and heart failure in the conservative group during hospitalization were significantly higher than those in the intervention group (P <0.05). The rates of ischemic rebleeding, malignant arrhythmia, cardiac arrhythmia (P0.05). There was no significant difference in bleeding rate between the two groups (P> 0.05). The rates of ischemic rebleeding, malignancy The incidence of arrhythmia, heart failure and death was higher in the conservative group than in the intervention group (P <0.05). There was no significant difference in the bleeding rate between the two groups (P> 0.05). Conclusion In the treatment of elderly high-risk women with NSTEMI, early invasive treatment is safe and effective.