有关肥胖症的生物控制机制的研究,虽然在动物模型及某些先天畸形综合征中获得成功,但在人群的发生机制研究上,却一直少有进展。本文作者研究指出,月经初潮时间是成年时代早期体重增加和肥胖的一个主要的决定因素。资料来源于两个研究项目。研究对象为年龄在20～24岁之间的16868名年轻成年白人妇女。按月经初潮年龄分为早(11岁或以下)、中(12～13岁)、晚(14岁或以上)三组。除了收集关于身高、体重、社会经济状况的资料外,人体测量学方面的指标包括三头肌、肩胛 Research on the mechanism of biological control of obesity, although successful in animal models and in some cases of congenital malformation syndrome, has seen little progress in the study of the mechanism of the population. The authors study indicates that menarche is a major determinant of weight gain and obesity in early adulthood. Data from two research projects. The study population was 16868 young adult white women aged 20 to 24 years old. According to menarche age divided into early (11 years old or below), middle (12 to 13 years old), late (14 years old or above) three groups. In addition to collecting data on height, weight and socioeconomic status, anthropometric metrics include triceps, scapular