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目的:探讨莱菔子水溶性生物碱对高脂血症小鼠SOD及MDA指标的影响。方法:取ApoE基因敲除小鼠的血清,观察莱菔子水溶性生物碱对小鼠SOD及MDA指标的影响。结果:莱菔子水溶性生物碱可有效降低小鼠血清MDA含量,升高SOD水平。结论:莱菔子水溶性生物碱可阻止血脂升高,保护动脉内皮细胞,清除自由基,抑制脂质过氧化,从而对抗动脉粥样硬化的形成,是治疗和预防高脂血症和动脉粥样硬化理想药物。
Objective: To investigate the effect of water-soluble alkaloids from radix islamicus on SOD and MDA in hyperlipidemic mice. Methods: ApoE knockout mice were taken serum to observe the effect of water-soluble alkaloids of Radish on mice SOD and MDA. Results: Radish seed water-soluble alkaloids can effectively reduce the serum MDA content and increase the level of SOD. Conclusion: Radix Puerariae alkaloids can prevent hyperlipidemia, protect arterial endothelial cells, scavenge free radicals, inhibit lipid peroxidation and thus antagonize the formation of atherosclerosis, which is the treatment and prevention of hyperlipidemia and atherosclerosis Hardened ideal medicine.