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目的:探析腹腔镜胃癌根治术治疗胃癌的疗效和安全性。方法:本研究随机选取我院2011年4月~2013年4月期间收治的104例胃癌患者为研究对象,采用随机数字法将其分为2组,对照组56例采用传统开腹胃癌根治术,治疗组48例采用腹腔镜胃癌根治术,观察两组切口长度、术中出血量、手术时间、胃肠道恢复时间、淋巴结清扫数、住院时间、免疫指标水平、并发症等情况。结果:治疗组患者手术切口、术中出血量、胃肠道恢复时间、住院时间等均小于对照组(P<0.05);淋巴结清扫数比较差异不显著(P>0.05),外周血T淋巴细胞亚群以及NK细胞活性均明显高于对照组(P<0.05);并发症发生率明显低于对照组(P<0.05)。结论:腹腔镜胃癌根治术治疗胃癌疗效显著,具有微创、出血量少、术后恢复快等优势,值得在临床上广泛推广和应用。
Objective: To investigate the efficacy and safety of laparoscopic radical gastrectomy for gastric cancer. Methods: 104 gastric cancer patients admitted to our hospital from April 2011 to April 2013 were randomly selected for the study. Random number method was used to divide the patients into two groups. 56 patients in the control group were treated with conventional open radical gastrectomy 48 cases in the treatment group were treated with laparoscopic radical gastrectomy. The incision length, intraoperative blood loss, operation time, gastrointestinal tract recovery time, number of lymph node dissection, length of hospital stay, level of immune indicators and complications were observed. Results: The surgical incision, intraoperative blood loss, gastrointestinal tract recovery time and hospital stay in the treatment group were all less than those in the control group (P <0.05). There was no significant difference in the number of lymph node dissection between the two groups (P> 0.05) Subpopulation and NK cell activity were significantly higher than the control group (P <0.05); the incidence of complications was significantly lower than the control group (P <0.05). Conclusions: Laparoscopic radical gastrectomy for gastric cancer has significant curative effect. It has the advantages of minimal invasion, less bleeding and quick recovery after operation. It is worthy of wide application in clinic.