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根据祖国医学理论，选择符合中医六淫病因学说的造模因素，模拟自然潮湿环境，将动物分为外湿组、湿热组、寒湿组、寒冷组、湿热组和正常对照组。于造模第１２天、４０天、１０８天时进行大鼠关节、肺、大小肠、肝等病理学研究。结果发现均存在不同程度的病理形态学和超微结构的改变。随着造模时间的延长逐渐加重。提示外湿致病确有其病理学基础。
According to the medical theory of the motherland, we select the modeling factors that conform to the theory of the cause of the six Chinese traditional Chinese medicines to simulate the natural wet environment. The animals were divided into external wetness, dampness, cold and dampness, cold, dampness and normal control groups. On the 12th day, 40th day and 108th day of the model establishment, the pathological study of the joints, lungs, intestines, and liver of the rats was conducted. The results showed that there are varying degrees of pathological and ultrastructural changes. With the extension of modeling time gradually increased. Tip wet disease does have its pathological basis.