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目的研究核酪联合阿奇霉素序贯疗法治疗小儿支原体肺炎(MPP)的疗效。方法将36例支原体肺炎患儿随机分为观察组与对照组,每组18例,观察组采用核酪联合阿奇霉素序贯治疗,对照组采用红霉素治疗。结果观察组治愈17例(94.4%),总有效率为100%;对照组治愈12例(66.7%),总有效率为77.8%,观察组治愈率明显优于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率为11.1%,对照组不良反应发生率为38.9%,两组比较差异有统计学意义(P<0.01)。结论核酪联合阿奇霉素序贯治疗小儿支原体肺炎安全经济有效,值得推广应用。
Objective To study the effect of combined chemotherapy with azithromycin on children with mycoplasma pneumonia (MPP). Methods Thirty-six children with mycoplasma pneumonia were randomly divided into observation group and control group, with 18 cases in each group. The observation group was treated with sequential combined azithromycin and cheese, and the control group was treated with erythromycin. Results The observation group was cured in 17 cases (94.4%), the total effective rate was 100%. The control group was cured in 12 cases (66.7%), the total effective rate was 77.8%. The cure rate in the observation group was significantly better than that in the control group (P <0.05). The incidence of adverse reactions in the observation group was 11.1%, and the incidence of adverse reactions in the control group was 38.9%. There was significant difference between the two groups (P <0.01). Conclusion Combination of cheese and azithromycin sequential treatment of children with mycoplasma pneumonia is safe and economical, it is worth to promote the application.