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用荧光法测定４７例急性脑卒中患者血清５－羟色胺（５－ＨＴ）含量。脑梗塞患者５－ＨＴ含量是１３８．３２±５４．５４μｇ／Ｌ，脑出血患者５－ＨＴ含量是１７７．２６±７８．９６μｇ／Ｌ，均明显高于对照组的１０８．１０±３８．３０μｇ／Ｌ，脑梗塞组与脑出血组差异无显著性。重型、大量出血或大面积梗塞并伴有持续血压升高的患者血清５－ＨＴ含量升高更为明显，提示血清５－ＨＴ持续升高的脑卒中患者预后不良。
Serum 5-hydroxytryptamine (5-HT) levels in 47 patients with acute stroke were measured by fluorometry. The content of 5-HT in patients with cerebral infarction was 138.32 ± 54.54μg / L, and the content of 5-HT in patients with cerebral hemorrhage was 177.26 ± 78.96μg / L, which were significantly higher than 108.10 ± 38.30μg / L, cerebral infarction group and cerebral hemorrhage group no significant difference. Serum 5-HT levels are more pronounced in patients with heavy, massive bleeding, or extensive infarction with persistent high blood pressure, suggesting a poor prognosis in stroke patients with elevated serum 5-HT.