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作者观察了15例正常妊娠,孕39周临产前行选择性剖腹产。术前口服微粒化天然孕激素400mg 同时末稍静脉取血,100～300分钟后在术中再次取血。胎儿娩出后在宫体肌层4个不同部位取活检:非胎盘附着处近浆膜者为Ⅰ,近内膜者为Ⅱ,胎盘附着部位近浆膜者为Ⅲ,近内膜者为Ⅳ。立即测定孕激素,17β-强力求偶素和雌酮水平。孕激素变化:血浆水平在口服后约150分钟增加到峰值,在其后100分钟内降到最低,约240分钟时恢复到对照水平。4个不同部位子宫肌活组织内孕激素120～160分钟达最高值,超出对照范围,60分钟后降到正常水平以下,约在服药后240分钟恢
The authors observed 15 normal pregnancies and 39 weeks of prenatal selective caesarean section. Preoperative oral micronized natural progestin 400mg at the same time a little intravenous blood, 100 to 300 minutes after surgery in the blood again. After the fetus was delivered, biopsies were taken from 4 different parts of the uterine myometrium: those with near serosal non-placental attachment were Ⅰ, those with proximal intima as Ⅱ, and those with near-serosal attachment as placental Ⅲ and Ⅳ as proximal intima. Immediate determination of progesterone, 17β-forgone and estrone levels. Progestin changes: Plasma levels peaked at about 150 minutes after oral administration, reached a minimum within 100 minutes thereafter, and returned to control levels at about 240 minutes. 4 different parts of uterine muscle tissue progesterone within 120 to 160 minutes reached the highest value beyond the control range, 60 minutes later dropped to below normal levels, about 240 minutes after taking the medicine