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暗色丝孢霉病是由具褐色菌丝壁的真菌引起的皮下真菌病,很少感染肌肉骨骼。作者在巴西首次报导1例由棘状外瓶霉引起的累及骨骼的皮下暗色丝孢霉病。12岁男性患者,右侧面部皮下脓肿伴肿痛,1年后左肘、指、趾出现新脓肿,持续已3年。病变为深部皮下脓肿,直径达数厘米,其中由增厚表皮所覆盖脓肿破裂后,可形成表皮溃疡,状似着色真菌病。局部淋巴结稍肿大,手术切除皮下肉芽作活检。检查示中心坏死区在切片时丢失,但HE及PAS染色可见短菌丝片断及中性粒细胞。脓液镜检可见大的菌丝状细胞,有些舌丝含有狭窄的管状菌细胞,于SDA 28℃及37℃培养7天后出现深
Dark silk mold disease is a subcutaneous mycosis caused by a fungus with a brown mycelial wall that rarely infects the musculoskeletal. The authors reported for the first time in Brazil 1 case of hypoplastic dark-colored silk mold disease involving the spine of Echinacea. A 12-year-old male patient had a subcutaneous abscess on the right side with swelling and pain and a new abscess in her left elbow, finger and toe after 1 year, which lasted for 3 years. Lesions for deep subcutaneous abscess, a few centimeters in diameter, which consists of thickening of the epidermis covered abscess rupture, the formation of epidermal ulcers, like colored fungal disease. Local lymph nodes slightly enlarged, surgical excision of subcutaneous granulation for biopsy. Check the center of necrosis showed loss of sections, but HE and PAS stain visible mycelial fragments and neutrophils. Pus revealed large myxoid cells microscopy, and some tongue contains narrow cells of tubular cells, SDA 28 ℃ and 37 ℃ after 7 days after the emergence of deep