小鼠经0、0.05、0.25、0.5、0.75和1.0Gy的X射线照射后7小时和60天,用快速制备小鼠外周血细胞染色体的方法观察了淋巴细胞染色体畸变与剂量的关系,并与骨髓细胞进行了比较。结果:早期两类细胞染色体畸变的剂量效应关系为直线相关,曲线斜率差异不显著,淋巴细胞畸变率略高;晚期,两类细胞染色体畸变率比早期的结果明显降低,除易位畸变与剂量为直线相关外,其它类型畸变与剂量无规律。比较两类细胞畸变率为骨髓细胞高。 Mice were exposed to 0,0.05,0.25,0.5,0.75 and 1.0 Gy X-rays 7 and 60 days after the rapid preparation of mouse peripheral blood cell chromosome was observed lymphocyte chromosome aberration and dose relationship with the bone marrow Cells were compared. Results: There was a linear correlation between the dose-response relationship of the two types of chromosomes in the early stage and the slope of the curve. The aberration rate of lymphatic cells was slightly higher. In the late stage, the chromosome aberration rate of the two types of cells was significantly lower than that of the early stage. For the linear correlation, other types of distortion and dose irregular. Comparison of two types of cell aberration rate of bone marrow cells.