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目的:研究上感口服液抗炎解热等药效作用,方法:观察上感口服液对二甲苯所致小鼠耳廓炎性肿胀的影响,对静脉注射脱脂牛奶致家兔发热的影响。对静脉注射刚果红后小鼠吞噬细胞吞噬功能的影响。以及对金黄色葡萄球菌、溶血性链球菌、白色葡萄球菌的体外抑制作用。结果:该药可抑制动物耳廓炎症,有较好的解热作用,可增强吞噬细胞功能,可明显抑制α溶血性链球菌、白色葡萄球菌生长。结论:上感口服液可拮抗急性渗出性炎症,增加非特异性免疫功能,有较好的解热、抑菌作用。
Objective: To study the anti-inflammatory, antipyretic, and other pharmacodynamic effects of Shanggan Oral Liquid. Methods: To observe the effect of Shanggan Oral Liquid on inflammatory swelling in the ear of mice induced by xylene and influence the fever induced by intravenous injection of skim milk. Effect of phagocytosis of phagocytic cells in mice following intravenous injection of Congo Red. And in vitro inhibition of Staphylococcus aureus, Streptococcus hemolyticus, Staphylococcus aureus. RESULTS: The drug can inhibit inflammation of the auricle in animals and has a good antipyretic effect. It can enhance the function of phagocytic cells and can significantly inhibit the growth of alpha hemolytic streptococci and staphylococcus. Conclusion: Shanggan oral liquid can antagonize acute exudative inflammation, increase non-specific immune function, and have good antipyretic and antibacterial effects.