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目的观察鼓室内注射地塞米松和鼓室正压治疗梅尼埃病的疗效。方法13例难治性梅尼埃病患者鼓室内注射地塞米松,首次剂量5mg,第2天再注射5mg,第2～4周每周注射5mg,同时配合鼓室正压治疗,检测眩晕、听力及耳鸣变化。结果13例随访2～5年,眩晕完全控制9例,明显减轻3例,眩晕6个月后复发,再治疗1个疗程后控制1例。耳鸣消失5例,减轻3例,无效5例,听力提高10～30dB9例,不变4例。结论鼓室内注射地塞米松配合间歇性鼓室正压治疗难治性梅尼埃病能有效地控制眩晕,其操作简单,费用低,患者易于接受。
Objective To observe the curative effect of intra-ventricular injection of dexamethasone and tympanum on Meniere’s disease. Methods Thirteen cases of refractory Meniere’s disease were infused intratumorally with dexamethasone. The first dose was 5 mg, the second injection was 5 mg, and the second to fourth weeks were injected with 5 mg weekly. Combined with tympanic positive pressure treatment, dizziness and hearing were detected And tinnitus changes. Results Thirteen cases were followed up for 2 to 5 years. 9 cases were completely controlled by vertigo, 3 cases were relieved obviously, 6 cases relapsed after 6 months’ dizziness, and 1 case was treated by one course of treatment. Tinnitus disappeared in 5 cases, 3 cases reduced, 5 cases ineffective, hearing increased 10 ~ 30dB9 cases, unchanged in 4 cases. Conclusion Intratympanic injection of dexamethasone in combination with intermittent tympanic positive pressure treatment of refractory Meniere’s disease can effectively control vertigo, its operation is simple, low cost, patients are easy to accept.