目的 :探讨山羊房室结组织的年龄变化规律。方法 :光镜、电镜观察和图像分析。结果 :老年羊房室结内一般心肌细胞增加 60 % ,细胞间质增多 3 0 % ,胶原纤维增多 2 0 % ,出现脂肪细胞。电镜下老年羊房室结细胞内可见较多的脂褐素 ,线粒体紊乱脱嵴 ,溶酶体膜破裂溶解。结论 :随着年龄增长 ,羊房室结、房室束和束支的组织学和亚显微结构出现一系列变化 Objective: To investigate the age variation of goats’ atrioventricular nodules. Methods: Light microscope, electron microscope observation and image analysis. Results: The average number of myocytes in the atrioventricular node increased by 60%, the interstitial cells increased by 30% and the collagen fibers increased by 20%. Adipocytes appeared. Electron microscopy showed more lipofuscin in the cells of the aged sheep atrophy, mitochondrial debridement and lysosomal membrane rupture. CONCLUSIONS: With age, there is a series of changes in the histology and sub-microstructure of sheep atrioventricular node, atrioventricular bundle and bundle branch