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目的:分析总结小儿支原体感染后咳嗽治疗中应用肺炎合剂联合阿奇霉素口服及雾化吸入的治疗效果。方法:以随机数字表法,将80例小儿支原体感染后咳嗽患儿分为两组,以接受包括阿奇霉素口服及布地奈德、异丙托溴铵溶液雾化吸入的西药治疗者为对照组,在以上治疗基础上加用肺炎合剂口服为治疗组,每组40例。对比两组临床治疗效果。结果:接受治疗2周后,治疗组支原体滴度≥1∶160例数低于对照组(P<0.05)。同时,2周治疗完成后,治疗组CRP、ESR、咳嗽、咳痰及发热评分均低于对照组(P<0.05)。此外,2周治疗完成后,治疗组治疗总有效率高于对照组(P<0.05),而治疗不良反应发生率比较,无统计学差异(P>0.05)。结论:肺炎合剂联合布地奈德可显著的改善小儿支原体感染后咳嗽的治疗效果。
Objective: To summarize the therapeutic effect of oral administration of pneumonia mixture and azithromycin inhalation in the treatment of cough after infection of children with mycoplasma. Methods: A random number table method, 80 cases of children with chronic mycoplasma infection of cough were divided into two groups to accept azithromycin, including oral and budesonide, ipratropium bromide solution inhalation of Western medicine as a control group, In addition to the above treatment with pneumonia mixture oral treatment group, 40 cases in each group. Comparison of two groups of clinical treatment. Results: After 2 weeks of treatment, the number of Mycoplasma titers≥1: 160 in treatment group was lower than that in control group (P <0.05). At the same time, the CRP, ESR, cough, sputum and fever scores in the treatment group were lower than those in the control group after 2 weeks of treatment (P <0.05). In addition, after 2 weeks of treatment, the total effective rate of the treatment group was higher than that of the control group (P <0.05), while the incidence of adverse reactions was no significant difference (P> 0.05). Conclusion: Combination of pneumonia and budesonide can significantly improve the therapeutic effect of cough in children with mycoplasma infection.