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16例7～13岁的哮喘儿童随机分为2组,治疗组服硫酸麻黄素25毫克,对照组服安慰剂,均8小时一次,连续8周,用双盲法评价麻黄素与茶碱联用的疗效,毒性和出现耐受性。根据肺功能测定资料确定支气管扩张反应的程度和持续时间,将晨6时应用茶碱后推测的血峰浓度测定作为基线,以第1周和第8周值的平均变化百分比绘成曲线。16例病儿正常强力呼气量(FEV_1)与最
Sixteen asthmatic children aged 7 to 13 years old were randomly divided into two groups. The treatment group received 25 mg of ephedrine sulfate. The control group took placebo for 8 hours. After 8 weeks of continuous treatment, the ephedrine and theophylline groups Efficacy, toxicity and tolerability. The degree and duration of bronchodilation were determined according to the pulmonary function test data. The baseline peak blood presusivance measured after 6 weeks of application of theophylline was plotted as the mean percentage change from week 1 to week 8 values. 16 cases of children with normal strong expiratory volume (FEV_1) and the most