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目的探讨重症肾功能衰竭伴多器官衰竭(MODS)患者实施连续肾替代抢救治疗(CRRT)的临床效果。方法选取2011年6月至2013年6月连云港市第一人民医院肾功能衰竭患者40例,随机分为普通组和治疗组,普通组实施常规治疗,治疗组在常规治疗基础上实施CRRT治疗,对比两组治疗后尿素氮、血二氧化碳、血钾、肌酐、血氯、血钠等指标。结果普通组患者死亡10例(50.00%),治疗组患者死亡6例(30.00%),治疗组死亡率明显低于普通组(P<0.05);治疗组治疗后血肌酐、血尿素氮、血钾、血钠、血氯、血二氧化碳均有明显改善,优于普通组,差异有统计学意义(P<0.05)。结论重症肾功能衰竭伴多器官衰竭患者实施连续肾替代抢救治疗的临床效果显著,可以有效提升抢救成功率。
Objective To investigate the clinical effect of continuous renal replacement therapy (CRRT) in patients with severe renal failure and multiple organ failure (MODS). Methods 40 patients with renal failure in Lianyungang First People’s Hospital from June 2011 to June 2013 were randomly divided into general group and treatment group. The general group was given routine treatment. The treatment group was treated with CRRT on the basis of routine treatment, The two groups were compared after treatment urea nitrogen, blood carbon dioxide, potassium, creatinine, blood chlorine, serum sodium and other indicators. Results The death rate of the common group was 10.00%, while that of the treatment group was 6.00%. The death rate of the treatment group was significantly lower than that of the common group (P <0.05). The serum creatinine, blood urea nitrogen, blood Potassium, serum sodium, blood chlorine, blood carbon dioxide were significantly improved, better than the normal group, the difference was statistically significant (P <0.05). Conclusion The clinical effect of continuous renal replacement therapy in patients with severe renal failure and multiple organ failure is significant, which can effectively improve the success rate of rescue.