目的与常温下治疗高血压脑出血术后患者临床效果相比较,探讨亚低温对患者的临床效果。方法选取100例高血压脑出血术后患者,分为亚低温组(50例)和常温对照组(50例),亚低温组术后开始用冰毯机持续降温,维持体温32℃～35℃。配合应用冬眠、镇静、解痉等措施,治疗时间为5～7d。对照组患者给予常规治疗,措施与亚低温组相同。两组患者伤后当天及第1,3,5,7天行头颅CT扫描检查,动态观察损伤脑组织的影像学变化,并作预后分析。结果治疗后3～6个月后,亚低温组恢复良好率为19/50(38%),死亡率4/50(8%)。对照组恢复良好率为12/50(24%),死亡率7/50(14%)。两组比较,差异均有显著性意义(P<0.01)。结论亚低温治疗可以降低高血压脑出血手术患者的死亡率,改善预后,是治疗高血压脑出血患者的有效辅助方法。 Objective To compare the clinical effects of hypertensive intracerebral hemorrhage (ICH) patients treated at room temperature and explore the clinical effect of mild hypothermia on patients. Methods 100 patients with hypertensive intracerebral hemorrhage after operation were divided into mild hypothermia group (n = 50) and normal temperature control group (n = 50). The hypothermia group began to cool down with ice blanket machine after operation and maintained the body temperature of 32 ℃ ~ 35 ℃ . With the application of hibernation, sedation, antispasmodic and other measures, the treatment time is 5 ~ 7d. Control group patients given conventional treatment, the same measures and mild hypothermia. Two groups of patients on the day after injury and on the 1st, the 1st, the 5th, the 5th and the 7th day underwent cranial CT scan examination. The dynamic changes of the brain tissue were observed and the prognosis was analyzed. Results After 3 to 6 months of treatment, the rate of good recovery in the mild hypothermia group was 19/50 (38%) and the mortality rate was 4/50 (8%). The rate of good recovery in the control group was 12/50 (24%) and the mortality rate was 7/50 (14%). The differences between the two groups were significant (P <0.01). Conclusion Mild hypothermia can reduce mortality and improve prognosis in patients with hypertensive intracerebral hemorrhage. It is an effective adjunct to patients with hypertensive intracerebral hemorrhage.