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地方性氟中毒病区多数为贫困地区,钙及其他营养素的摄入量明显不足,再加上摄入过量氟与体内的钙结合形成氟化钙血钙降低,所以氟中毒患者经常出现头痛、头晕、手抽、手麻和弯腰驼背等症状和体征。 作者选择饮用水含氟量为3.75mg/L的沧州市为调查点。8～12岁儿童氟斑牙患病率为76.7％,成人氟骨症检出率为7.4％,共测定了441例受试者;对照点选择在外界环境和营养状况与调查点相近的河北省新城县白沟镇涞远村,饮水含氟量0.9mg/L,8～12岁儿童氟斑牙患病率18.9％,成人氟骨症检出率0％,共检查了240名受试者。 晨起空腹采静脉血,低温高速离心分离血清,保存于-20℃,用瑞士产COBAS FARA型离心式全自
Fluorosis in endemic areas most of the poor areas, the intake of calcium and other nutrients was significantly inadequate, coupled with excess fluoride and calcium in the body to form calcium fluoride calcium decreased, so patients with fluorosis often headache, Dizziness, hand pumping, hand numbness and hunched over and other symptoms and signs. The author chose drinking water fluorine content of 3.75mg / L of Cangzhou as a survey point. The prevalence of dental fluorosis in children aged 8 ~ 12 years was 76.7%, and the detection rate of adult skeletal fluorosis was 7.4%. A total of 441 subjects were tested. Control points were selected in Hebei Province with similar environmental and nutritional status Province Xincheng County Baigou Zhen Yuan farms, drinking water fluoride content 0.9mg / L, children aged 8 to 12 dental fluorosis prevalence rate of 18.9%, adult skeletal fluorosis detection rate of 0%, a total of 240 subjects were examined By. Morning fasting venous blood, high-speed centrifugation of serum at low temperature, stored at -20 ℃, with Swiss-made COBAS FARA centrifugal self